TIMP2 抗体
Quick Overview for TIMP2 抗体 (ABIN6568761)
抗原
See all TIMP2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human TIMP2 (NP_003246.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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别名
- TIMP2
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背景
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
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分子量
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Observed_MW: 22kDa
Calculated_MW: 24kDa
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基因ID
- 7077
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UniProt
- P16035
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途径
- cAMP Metabolic Process
抗原
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